Ellen DeGeneres has sent “all of my love” to the family and friends of Anne Heche, following the actress’ serious car accident last week.

Heche remains on life support to see if she is a potential match for organ donation but has been classified as “legally dead according to California law,” her representative has said.

US talk show host DeGeneres, who dated the actress from 1997 to 2000, said it was a “sad day” following the news.

The 20th Annual Sir Elton John Oscar Party – Los Angeles
The 53-year-old was taken to hospital following the crash in the Mar Vista area of Los Angeles (Tony Di Maio/PA)

The 53-year-old was taken to hospital following the crash in the Mar Vista area of Los Angeles and suffered a “severe anoxic brain injury”.

Posting to her social media, DeGeneres, 64, wrote: “This is a sad day.

“I’m sending Anne’s children, family and friends all of my love.”

Other celebrities including Heche’s other former partner James Tupper and Dancing With The Stars judge Carrie Ann Inaba paid tribute to Heche following the developments.

Tupper, who shares a son with the actress, posted a picture of her to Instagram with the caption “love you forever”.

Inaba tweeted: “May your soul be at peace. We will miss your beautiful, unique and free spirited energy.

“I will always remember your performance on @officialdwts in that costume, dancing with all your heart.

“Thank you for being you.”

Earlier, a representative of the actress told the PA news agency: “While Anne is legally dead according to California law, her heart is still beating, and she has not been taken off life support so that One Legacy (a national organ recovery organisation) can see if she is a match for organ donation.”

Following the update on her medical status, a statement on behalf of Heche’s family and friends said: “Today we lost a bright light, a kind and most joyful soul, a loving mother, and a loyal friend.

“Anne will be deeply missed but she lives on through her beautiful sons, her iconic body of work, and her passionate advocacy.

“Her bravery for always standing in her truth, spreading her message of love and acceptance, will continue to have a lasting impact.”

Her family had previously said it had “long been her choice to donate her organs”.

The Los Angeles Police Department (LAPD) previously confirmed to PA that the crash was being investigated as a felony driving-under-the-influence (DUI) traffic collision.

An LAPD spokesman said preliminary blood tests had revealed the presence of drugs in Heche’s system, but added that additional testing was required to rule out any substances that were administered in the hospital.

On Friday, a statement shared with PA on behalf of her family said the actress was “not expected to survive” the incident.

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Her family previously said it had ‘long been her choice to donate her organs’ (Ian West/PA)

“We want to thank everyone for their kind wishes and prayers for Anne’s recovery and thank the dedicated staff and wonderful nurses that cared for Anne at the Grossman Burn Centre at West Hills hospital,” the statement read.

“Unfortunately, due to her accident, Anne Heche suffered a severe anoxic brain injury and remains in a coma, in critical condition. She is not expected to survive,” it added.

Heche is known for films including Donnie Brasco, Six Days, Seven Nights, Cedar Rapids and the 1998 Psycho remake.

American actor Harrison Ford and actress Anne Heche in the movie 6 Days 7 Nights, USA 1998
Harrison Ford and Anne Heche in the movie Six Days, Seven Nights in 1998 (Alamy/PA)

Pictures and video footage obtained by US media outlet TMZ following the incident showed Ms Heche driving a blue Mini Cooper, which was later pictured severely damaged at the scene.

The vehicle struck a two-storey home and “erupted in heavy fire”, according to the Los Angeles Fire Department (LAFD).

Fifty-nine firefighters took 65 minutes to access, confine and fully extinguish the flames within the heavily damaged structure, according to an LAFD report.

Heche sustained a “significant pulmonary injury requiring mechanical ventilation” and “burns that require surgical intervention”, a spokeswoman for the actress previously confirmed to PA.